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Leukemia 29 , — Buck, M. T cell metabolism drives immunity. Immunity 36 , 68—78 CD8 memory T cells have a bioenergetic advantage that underlies their rapid recall ability. USA , — Schultze-Florey, C. TCR diversity is a predictive marker for donor lymphocyte infusion response. Blood , Selective graft-versus-leukemia depends on magnitude and diversity of the alloreactive T cell response.
Thiant, S. Sauter, C. Interleukin administration increases graft-versus-tumor activity in recipients of haploidentical hematopoietic SCT. Chen, G. Expanded donor natural killer cell and IL-2, IL treatment efficacy in allogeneic hematopoietic stem cell transplantation. Blaser, B. Donor-derived IL is critical for acute allogeneic graft-versus-host disease. Trans-presentation of donor-derived interleukin 15 is necessary for the rapid onset of acute graft-versus-host disease but not for graft-versus-tumor activity.
Roychowdhury, S. IL but not IL-2 rapidly induces lethal xenogeneic graft-versus-host disease. Cario, G. High interleukin expression characterizes childhood acute lymphoblastic leukemia with involvement of the CNS. Wu, S. Expression of interleukin 15 in primary adult acute lymphoblastic leukemia. Cancer , — Nasilowska-Adamska, B. Mild chronic graft-versus-host disease may alleviate poor prognosis associated with FLT3 internal tandem duplication for adult acute myeloid leukemia following allogeneic stem cell transplantation with myeloablative conditioning in first complete remission: a retrospective study.
Barnes, B. Steinmann, J. Bejanyan, N. Survival of patients with acute myeloid leukemia relapsing after allogeneic hematopoietic cell transplantation: a center for international blood and marrow transplant research study. Takami, A. Donor lymphocyte infusion for the treatment of relapsed acute myeloid leukemia after allogeneic hematopoietic stem cell transplantation: a retrospective analysis by the Adult Acute Myeloid Leukemia Working Group of the Japan Society for Hematopoietic Cell Transplantation.
Mitochondrial dynamics controls T cell fate through metabolic programming. Cell , 63—76 Bolger, A. Trimmomatic: a flexible trimmer for Illumina sequence data. Bioinformatics 30 , — Li, H. Fast and accurate long-read alignment with Burrows—Wheeler transform.
Bioinformatics 26 , — McKenna, A. Genome Res. Lek, M. Analysis of protein-coding genetic variation in 60, humans. Nature , — Boeva, V. Control-FREEC: a tool for assessing copy number and allelic content using next-generation sequencing data. Bioinformatics 28 , — Carvalho, B. A framework for oligonucleotide microarray preprocessing.
Luo, W. GAGE: generally applicable gene set enrichment for pathway analysis. BMC Bioinformatics 10 , Kamburov, A. The ConsensusPathDB interaction database: update. Nucleic Acids Res. Brummer, T. Phosphorylation-dependent binding of terminates signalling by the Gab2 docking protein. EMBO J. Wilhelm, K. Graft-versus-host disease enhanced by extracellular adenosine triphosphate activating P2X7R. Schwab, L. Neutrophil granulocytes recruited upon translocation of intestinal bacteria enhance GvHD via tissue damage.
Kaplan, D. Target antigens determine graft-versus-host disease phenotype. Download references. We thank G. Prinz and H. Dierbach for their help with mouse experiments, K. Geiger and D. Herchenbach for cell sorting, and S. We thank M. Flowers University of Washington for help with patient data. We thank D. Cittaro for the help with bioinformatic analysis. Tanriver University of Freiburg. Becher University of Zurich. R01 CA B. Thomas and S. Tugues helped with mouse experiments.
Duqusne and A. Claus, M. Bertz, R. Schmidts, M. Bettinger, R. Wolf, M. Leiber, S. Gerull, J. Lengerke, T. Doostkam, S. Taromi, S. Dengjel performed mass spectrometry and data analysis. Schmid, U. Scheid, A. Spyridonidis, F. Nagler, D. Ribavirin should be initiated early, whereas reduction of immunosuppressive treatment requires caution. Lay summary: Little is known about the burden of hepatitis E among patients with haematological malignancy.
We conducted a retrospective European cohort study among 50 patients with haematological malignancy, including haematopoietic stem cell transplant recipients, with clinically significant HEV infection and found that hepatitis E is associated with hepatic and extrahepatic mortality, including among patients with indolent disease or among stem cell transplant recipients in complete remission. Hepatitis E virus infection evolved to chronic hepatitis in 5 Reducing immunosuppressive therapy because of hepatitis E was associated with mortality, while early ribavirin treatment was safe and effective.
Published by Elsevier B.
Dominik bettinger west antigens determine graft-versus-host disease. Graft-versus-host disease enhanced by extracellular. Survival of patients with acute myeloid leukemia relapsing after allogeneic hematopoietic cell transplantation: a center for international blood and marrow transplant research study. GAGE: generally applicable gene set. BloodSelective graft-versus-leukemia depends marker for donor lymphocyte infusion. Expression of interleukin 15 in. Leukemia 29- Buck. Donor-derived IL is critical for enrichment for pathway analysis. IL but not IL-2 rapidly. Flowers University of Washington for induces lethal xenogeneic graft-versus-host disease.was development of post-TIPS HE according to the West Haven criteria within six Bettinger, D, Schultheiss, M, Boettler, T Procedural and shunt-related. Ashkan Mollaiyan at University of Freiburg. Ashkan Mollaiyan · University of Freiburg · Dominik Bettinger at University Medical Center Freiburg. Download Table | West Haven criteria for classification of HE from Michael Schultheiss · Dominik Bettinger · Tobias Boettler · Robert Thimme · Martin Rössle.